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Transplant for FRCS (Gen Surg)

Transplantation is a small domain, examined at the level a general surgeon needs: recognising the early complications of a transplant, understanding the drugs these patients take, and knowing the principles of organ donation and dialysis access. It covers transplant immunology and rejection, immunosuppressive drugs and their toxicities, organ donation after brain-stem and circulatory death and organ retrieval, kidney, pancreas and liver transplantation, and arteriovenous fistulas, grafts and peritoneal dialysis access.

25 questions in the bank · 1 topics Updated 12 November 2026

Topics in this domain

  • Transplantation & dialysis access25

What the paper tends to test

  • Early complication questions describe a fall in urine output or a rising creatinine after a kidney transplant and ask for the cause or the next test.
  • Immunosuppression questions test drug toxicities and interactions.
  • Access questions test the choice and maturation of a fistula and the management of its complications.

Classic traps and discriminators

  • Sudden anuria after a kidney transplant that had been working suggests a vascular thrombosis and needs urgent ultrasound.
  • Calcineurin inhibitors are nephrotoxic and interact with many common drugs, including macrolide antibiotics and azole antifungals.

Free transplant practice question

From the free sample — original, referenced, with the full explanation. Rate your confidence first.

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A 48-year-old man with a kidney transplant, stable on tacrolimus, mycophenolate mofetil and prednisolone, is treated by his general practitioner for a chest infection. A week later he has a coarse tremor, potassium 6.1 mmol/L and a creatinine that has risen from 110 to 205 µmol/L.

Which antibiotic is most likely to be responsible?

How sure are you?

Transplant questions, answered

Is transplant surgery examined in detail?

No. It is a small part of the syllabus, examined at the level of the general surgeon who may admit a transplant patient or need to understand their treatment.

Drill transplant tonight

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